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Dear Mary Jane
The Shift
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Start Here
About
Dear Mary Jane
The Shift
Members
Blog
Login Account
Research: Simply Explained cole pethybridge 2026-11-04 Research: Simply Explained cole pethybridge 2026-11-04

THC & Alcohol Craving: A Surprising RCT

Cannabis and alcohol are the two most used substances in the world — but how do they actually interact? A 2026 randomized controlled trial gave participants controlled doses of THC and then measured their alcohol craving and consumption. The results were surprising. Here's the breakdown.

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Research: Simply Explained cole pethybridge 2026-10-28 Research: Simply Explained cole pethybridge 2026-10-28

CBD & Depression: What Lab Research Shows (and Doesn't)

People use cannabis for low mood more than almost any other reason — but what does the science actually show? A 2026 meta-analysis of 123 animal studies gives us the most comprehensive look yet at the biological evidence for CBD and depression. Here's what it means — and what it doesn't.

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Research: Simply Explained cole pethybridge 2026-10-21 Research: Simply Explained cole pethybridge 2026-10-21

Cannabis & Inflammatory Bowel Disease

Between 11% and 17% of Crohn's and colitis patients use cannabis for symptom management. A 2026 systematic review looked at what the science actually shows about THC-containing cannabis and inflammatory bowel disease. The findings are more nuanced than most people realize.

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Research: Simply Explained cole pethybridge 2026-10-14 Research: Simply Explained cole pethybridge 2026-10-14

Cannabis & Multiple Sclerosis Spasticity

Multiple sclerosis-related muscle spasticity affects most people with MS and is often poorly managed. A 2026 systematic review analyzed 27 randomized trials and over 3,000 patients to find out what cannabis actually does for it. Here's what the strongest evidence yet actually shows.

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Research: Simply Explained cole pethybridge 2026-10-07 Research: Simply Explained cole pethybridge 2026-10-07

CBD & Jaw Pain: A Randomized Trial

Jaw pain affects millions of people worldwide and is notoriously hard to treat. A 2026 randomized trial became the first to test oral CBD specifically for this condition. The results weren't what many expected — here's what they actually found and what it means.

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Educational content only. Not medical advice.